The Focusrite Pro ISA ADN2 is two-channel A-D card that provides high-quality analog-to-digital conversion for the ISA One microphone preamp and DI. Capable of operating at sample rates up to 24-bit / 192 kHz, the card features S/PDIF, AES3, Dante, and ADAT connectivity. The Dante outputs provide network connectivity to all Focusrite RedNet devices and Red interfaces, as well as any other Dante-enabled devices. Routing is configured using Dante Controller, while metering and settings are accessed through RedNet Control.

Connections include primary and secondary RJ45 Dante output ports, an XLR connector for AES3 output, a TOSLINK connector for the ADAT output, and an RCA connector for S/PDIF output. Word Clock I/O on BNC connectors allows synchronization to multiple digital sources. This also includes syncing the Dante network to a house clock or sycing external equipment to the Dante network.